Coexpression cluster: Cluster_45 (Co-expression clusters of Perlo et al 2022 (PRJEB44480))

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0051603 proteolysis involved in protein catabolic process 14.46% (12/83) 4.51 0.0 0.0
GO:0006508 proteolysis 18.07% (15/83) 3.67 0.0 0.0
GO:0006511 ubiquitin-dependent protein catabolic process 12.05% (10/83) 4.73 0.0 0.0
GO:0019941 modification-dependent protein catabolic process 12.05% (10/83) 4.59 0.0 0.0
GO:0043632 modification-dependent macromolecule catabolic process 12.05% (10/83) 4.53 0.0 0.0
GO:1901575 organic substance catabolic process 16.87% (14/83) 3.29 0.0 0.0
GO:0009057 macromolecule catabolic process 13.25% (11/83) 3.87 0.0 0.0
GO:0009056 catabolic process 16.87% (14/83) 3.22 0.0 0.0
GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway 3.61% (3/83) 10.01 0.0 0.0
GO:0061630 ubiquitin protein ligase activity 8.43% (7/83) 5.01 0.0 0.0
GO:0061659 ubiquitin-like protein ligase activity 8.43% (7/83) 4.95 0.0 0.0
GO:0000151 ubiquitin ligase complex 8.43% (7/83) 4.98 0.0 0.0
GO:0004061 arylformamidase activity 3.61% (3/83) 9.41 0.0 0.0
GO:0006576 biogenic amine metabolic process 6.02% (5/83) 6.17 0.0 0.0
GO:0004197 cysteine-type endopeptidase activity 6.02% (5/83) 6.14 0.0 0.0
GO:0006569 tryptophan catabolic process 3.61% (3/83) 9.12 0.0 1e-06
GO:0042436 indole-containing compound catabolic process 3.61% (3/83) 9.12 0.0 1e-06
GO:0019441 tryptophan catabolic process to kynurenine 3.61% (3/83) 9.12 0.0 1e-06
GO:0070189 kynurenine metabolic process 3.61% (3/83) 9.08 0.0 1e-06
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 7.23% (6/83) 5.1 0.0 1e-06
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 6.02% (5/83) 5.84 0.0 1e-06
GO:1901564 organonitrogen compound metabolic process 28.92% (24/83) 1.8 0.0 1e-06
GO:0140535 intracellular protein-containing complex 10.84% (9/83) 3.6 0.0 1e-06
GO:0009308 amine metabolic process 6.02% (5/83) 5.47 0.0 2e-06
GO:0008150 biological_process 55.42% (46/83) 0.99 0.0 2e-06
GO:0004842 ubiquitin-protein transferase activity 8.43% (7/83) 4.15 0.0 3e-06
GO:0019787 ubiquitin-like protein transferase activity 8.43% (7/83) 4.1 0.0 3e-06
GO:0016755 aminoacyltransferase activity 8.43% (7/83) 4.07 0.0 4e-06
GO:1901565 organonitrogen compound catabolic process 9.64% (8/83) 3.65 0.0 4e-06
GO:0005575 cellular_component 44.58% (37/83) 1.16 0.0 5e-06
GO:0005737 cytoplasm 16.87% (14/83) 2.39 0.0 6e-06
GO:0015171 amino acid transmembrane transporter activity 6.02% (5/83) 5.07 0.0 6e-06
GO:0006865 amino acid transport 6.02% (5/83) 5.05 1e-06 7e-06
GO:0046943 carboxylic acid transmembrane transporter activity 6.02% (5/83) 4.96 1e-06 9e-06
GO:0005342 organic acid transmembrane transporter activity 6.02% (5/83) 4.96 1e-06 9e-06
GO:0050126 N-carbamoylputrescine amidase activity 2.41% (2/83) 10.5 1e-06 1e-05
GO:1990234 transferase complex 9.64% (8/83) 3.38 1e-06 1.4e-05
GO:0046942 carboxylic acid transport 6.02% (5/83) 4.73 1e-06 1.6e-05
GO:0015849 organic acid transport 6.02% (5/83) 4.73 1e-06 1.6e-05
GO:0008514 organic anion transmembrane transporter activity 6.02% (5/83) 4.7 2e-06 1.8e-05
GO:0015711 organic anion transport 6.02% (5/83) 4.58 2e-06 2.6e-05
GO:0006807 nitrogen compound metabolic process 31.33% (26/83) 1.38 3e-06 3e-05
GO:0008234 cysteine-type peptidase activity 6.02% (5/83) 4.41 4e-06 4.3e-05
GO:0033388 putrescine biosynthetic process from arginine 2.41% (2/83) 9.36 4e-06 4.4e-05
GO:0019538 protein metabolic process 21.69% (18/83) 1.74 5e-06 5e-05
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 6.02% (5/83) 4.35 5e-06 5.1e-05
GO:0110165 cellular anatomical entity 38.55% (32/83) 1.13 6e-06 5.3e-05
GO:0006568 tryptophan metabolic process 3.61% (3/83) 6.42 7e-06 5.7e-05
GO:0042430 indole-containing compound metabolic process 3.61% (3/83) 6.42 7e-06 5.7e-05
GO:0006586 indolalkylamine metabolic process 3.61% (3/83) 6.42 7e-06 5.7e-05
GO:0042537 benzene-containing compound metabolic process 3.61% (3/83) 6.41 7e-06 5.7e-05
GO:0010498 proteasomal protein catabolic process 6.02% (5/83) 4.21 9e-06 7.1e-05
GO:1902494 catalytic complex 10.84% (9/83) 2.73 9e-06 7.7e-05
GO:0030163 protein catabolic process 6.02% (5/83) 4.09 1.3e-05 0.000103
GO:0051234 establishment of localization 15.66% (13/83) 2.01 1.9e-05 0.000144
GO:0009074 aromatic amino acid family catabolic process 3.61% (3/83) 5.93 1.8e-05 0.000145
GO:0016567 protein ubiquitination 7.23% (6/83) 3.43 2.2e-05 0.000168
GO:0071704 organic substance metabolic process 33.73% (28/83) 1.14 2.4e-05 0.000174
GO:0044238 primary metabolic process 32.53% (27/83) 1.18 2.3e-05 0.000174
GO:0007275 multicellular organism development 3.61% (3/83) 5.8 2.4e-05 0.000175
GO:1901605 alpha-amino acid metabolic process 6.02% (5/83) 3.88 2.6e-05 0.000181
GO:0051179 localization 15.66% (13/83) 1.96 2.7e-05 0.00019
GO:0032446 protein modification by small protein conjugation 7.23% (6/83) 3.35 3e-05 0.000205
GO:0009446 putrescine biosynthetic process 2.41% (2/83) 7.91 3.3e-05 0.00022
GO:0009445 putrescine metabolic process 2.41% (2/83) 7.91 3.3e-05 0.00022
GO:0043687 post-translational protein modification 8.43% (7/83) 2.94 3.9e-05 0.000252
GO:0071763 nuclear membrane organization 2.41% (2/83) 7.63 4.9e-05 0.000312
GO:0042180 cellular ketone metabolic process 3.61% (3/83) 5.45 4.9e-05 0.000314
GO:0006810 transport 14.46% (12/83) 1.96 5.7e-05 0.000354
GO:0008152 metabolic process 33.73% (28/83) 1.07 5.9e-05 0.000361
GO:0016746 acyltransferase activity 8.43% (7/83) 2.8 7.1e-05 0.000429
GO:0006596 polyamine biosynthetic process 2.41% (2/83) 7.14 9.8e-05 0.000587
GO:0070647 protein modification by small protein conjugation or removal 7.23% (6/83) 3.02 0.000106 0.000624
GO:0000095 S-adenosyl-L-methionine transmembrane transporter activity 2.41% (2/83) 6.9 0.000135 0.000788
GO:0015101 organic cation transmembrane transporter activity 2.41% (2/83) 6.77 0.000164 0.00094
GO:1901606 alpha-amino acid catabolic process 3.61% (3/83) 4.8 0.000183 0.000999
GO:0006525 arginine metabolic process 2.41% (2/83) 6.7 0.000179 0.000999
GO:0004175 endopeptidase activity 6.02% (5/83) 3.28 0.000177 0.001004
GO:0009072 aromatic amino acid metabolic process 3.61% (3/83) 4.81 0.000182 0.001008
GO:0140096 catalytic activity, acting on a protein 16.87% (14/83) 1.58 0.000217 0.001167
GO:0009063 amino acid catabolic process 3.61% (3/83) 4.71 0.000224 0.00119
GO:0003934 GTP cyclohydrolase I activity 1.2% (1/83) 11.82 0.000276 0.001452
GO:0006595 polyamine metabolic process 2.41% (2/83) 6.34 0.000296 0.001535
GO:0071705 nitrogen compound transport 7.23% (6/83) 2.68 0.000364 0.001868
GO:0031461 cullin-RING ubiquitin ligase complex 3.61% (3/83) 4.41 0.000406 0.002059
GO:0008270 zinc ion binding 7.23% (6/83) 2.65 0.000413 0.00207
GO:0032991 protein-containing complex 14.46% (12/83) 1.64 0.000437 0.002164
GO:0005635 nuclear envelope 2.41% (2/83) 6.02 0.000457 0.00224
GO:0006520 amino acid metabolic process 6.02% (5/83) 2.97 0.00048 0.002326
GO:0043170 macromolecule metabolic process 24.1% (20/83) 1.15 0.000487 0.002333
GO:0046700 heterocycle catabolic process 4.82% (4/83) 3.45 0.000519 0.002431
GO:0044270 cellular nitrogen compound catabolic process 4.82% (4/83) 3.45 0.000519 0.002431
GO:0016192 vesicle-mediated transport 6.02% (5/83) 2.88 0.000629 0.002915
GO:0005764 lysosome 2.41% (2/83) 5.73 0.000683 0.003131
GO:1901682 sulfur compound transmembrane transporter activity 2.41% (2/83) 5.69 0.000718 0.003258
GO:0032501 multicellular organismal process 3.61% (3/83) 4.07 0.00081 0.0036
GO:0019439 aromatic compound catabolic process 4.82% (4/83) 3.28 0.000804 0.00361
GO:1901361 organic cyclic compound catabolic process 4.82% (4/83) 3.26 0.000857 0.00377
GO:0000323 lytic vacuole 2.41% (2/83) 5.51 0.000918 0.003995
GO:0045721 negative regulation of gluconeogenesis 1.2% (1/83) 9.82 0.001104 0.004667
GO:0006111 regulation of gluconeogenesis 1.2% (1/83) 9.82 0.001104 0.004667
GO:0007039 protein catabolic process in the vacuole 1.2% (1/83) 9.82 0.001104 0.004667
GO:0009309 amine biosynthetic process 2.41% (2/83) 5.36 0.001135 0.004702
GO:0042401 biogenic amine biosynthetic process 2.41% (2/83) 5.36 0.001135 0.004702
GO:0048856 anatomical structure development 3.61% (3/83) 3.89 0.001147 0.004706
GO:0071702 organic substance transport 7.23% (6/83) 2.36 0.001178 0.004791
GO:0016020 membrane 15.66% (13/83) 1.38 0.001347 0.005425
GO:0032422 purine-rich negative regulatory element binding 1.2% (1/83) 9.5 0.00138 0.005509
GO:0016054 organic acid catabolic process 3.61% (3/83) 3.76 0.001493 0.005849
GO:0046395 carboxylic acid catabolic process 3.61% (3/83) 3.76 0.001493 0.005849
GO:0006729 tetrahydrobiopterin biosynthetic process 1.2% (1/83) 9.12 0.001794 0.006904
GO:0046146 tetrahydrobiopterin metabolic process 1.2% (1/83) 9.12 0.001794 0.006904
GO:0046914 transition metal ion binding 8.43% (7/83) 2.0 0.001888 0.0072
GO:0005743 mitochondrial inner membrane 2.41% (2/83) 4.88 0.00217 0.008204
GO:0003933 GTP cyclohydrolase activity 1.2% (1/83) 8.82 0.002208 0.008274
GO:0009064 glutamine family amino acid metabolic process 2.41% (2/83) 4.8 0.002428 0.009021
GO:0005615 extracellular space 2.41% (2/83) 4.78 0.002501 0.009215
GO:0008233 peptidase activity 6.02% (5/83) 2.42 0.002541 0.009281
GO:0032777 piccolo histone acetyltransferase complex 1.2% (1/83) 8.43 0.002897 0.010491
GO:0045912 negative regulation of carbohydrate metabolic process 1.2% (1/83) 8.36 0.003034 0.010808
GO:0006446 regulation of translational initiation 1.2% (1/83) 8.36 0.003034 0.010808
GO:0034657 GID complex 1.2% (1/83) 8.18 0.003447 0.01208
GO:0019866 organelle inner membrane 2.41% (2/83) 4.55 0.003422 0.012088
GO:0044282 small molecule catabolic process 3.61% (3/83) 3.29 0.003731 0.012763
GO:0044281 small molecule metabolic process 8.43% (7/83) 1.83 0.003674 0.012769
GO:0032502 developmental process 3.61% (3/83) 3.28 0.003778 0.012821
GO:0005846 nuclear cap binding complex 1.2% (1/83) 8.07 0.003723 0.012835
GO:0046872 metal ion binding 9.64% (8/83) 1.66 0.003914 0.013179
GO:0043169 cation binding 9.64% (8/83) 1.62 0.004583 0.015313
GO:0004430 1-phosphatidylinositol 4-kinase activity 1.2% (1/83) 7.69 0.004823 0.015868
GO:0010906 regulation of glucose metabolic process 1.2% (1/83) 7.69 0.004823 0.015868
GO:0016787 hydrolase activity 13.25% (11/83) 1.27 0.005629 0.01838
GO:0031966 mitochondrial membrane 2.41% (2/83) 4.17 0.00569 0.018438
GO:0019150 D-ribulokinase activity 1.2% (1/83) 7.21 0.006746 0.021536
GO:0022857 transmembrane transporter activity 8.43% (7/83) 1.66 0.006718 0.021608
GO:0000785 chromatin 2.41% (2/83) 4.02 0.006901 0.021871
GO:0043255 regulation of carbohydrate biosynthetic process 1.2% (1/83) 7.09 0.007294 0.022948
GO:0006082 organic acid metabolic process 6.02% (5/83) 2.04 0.007534 0.02303
GO:0046654 tetrahydrofolate biosynthetic process 1.2% (1/83) 7.07 0.007432 0.023043
GO:0043436 oxoacid metabolic process 6.02% (5/83) 2.04 0.00751 0.023119
GO:0019752 carboxylic acid metabolic process 6.02% (5/83) 2.05 0.007423 0.023183
GO:0005215 transporter activity 8.43% (7/83) 1.6 0.008616 0.026151
GO:0005845 mRNA cap binding complex 1.2% (1/83) 6.67 0.00976 0.029416
GO:0031967 organelle envelope 2.41% (2/83) 3.74 0.010079 0.029958
GO:0031975 envelope 2.41% (2/83) 3.74 0.010079 0.029958
GO:0051446 positive regulation of meiotic cell cycle 1.2% (1/83) 6.59 0.010307 0.030219
GO:0045836 positive regulation of meiotic nuclear division 1.2% (1/83) 6.59 0.010307 0.030219
GO:0044248 cellular catabolic process 4.82% (4/83) 2.24 0.010556 0.030741
GO:2000243 positive regulation of reproductive process 1.2% (1/83) 6.45 0.0114 0.032976
GO:0005773 vacuole 2.41% (2/83) 3.61 0.011934 0.03429
GO:0040020 regulation of meiotic nuclear division 1.2% (1/83) 6.35 0.012219 0.034647
GO:0019238 cyclohydrolase activity 1.2% (1/83) 6.35 0.012219 0.034647
GO:0000339 RNA cap binding 1.2% (1/83) 6.31 0.012492 0.03519
GO:0062014 negative regulation of small molecule metabolic process 1.2% (1/83) 6.3 0.012628 0.035343
GO:0009987 cellular process 28.92% (24/83) 0.65 0.013164 0.036603
GO:0017196 N-terminal peptidyl-methionine acetylation 1.2% (1/83) 6.12 0.014264 0.039409
GO:0006109 regulation of carbohydrate metabolic process 1.2% (1/83) 6.09 0.014536 0.039905
GO:0097602 cullin family protein binding 1.2% (1/83) 5.98 0.015761 0.042993
GO:0051445 regulation of meiotic cell cycle 1.2% (1/83) 5.95 0.016033 0.04346
GO:0009889 regulation of biosynthetic process 8.43% (7/83) 1.41 0.016247 0.043494
GO:0031326 regulation of cellular biosynthetic process 8.43% (7/83) 1.42 0.016188 0.043607
GO:0018206 peptidyl-methionine modification 1.2% (1/83) 5.88 0.016848 0.044277
GO:0046835 carbohydrate phosphorylation 1.2% (1/83) 5.88 0.016848 0.044277
GO:0006474 N-terminal protein amino acid acetylation 1.2% (1/83) 5.87 0.016984 0.044364
GO:0032993 protein-DNA complex 2.41% (2/83) 3.35 0.016754 0.044573
GO:0006357 regulation of transcription by RNA polymerase II 3.61% (3/83) 2.45 0.018058 0.046885
GO:0051785 positive regulation of nuclear division 1.2% (1/83) 5.73 0.018612 0.048035
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
No similar clusters found
Sequences (83) (download table)

InterPro Domains

GO Terms

CAZYmes

Family Terms