Coexpression cluster: Cluster_726 (Co-expression clusters of Perlo et al 2022 (PRJEB44480))

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0071840 cellular component organization or biogenesis 22.22% (14/63) 2.91 0.0 2e-06
GO:1904356 regulation of telomere maintenance via telomere lengthening 4.76% (3/63) 8.72 0.0 3e-06
GO:0032210 regulation of telomere maintenance via telomerase 4.76% (3/63) 8.72 0.0 3e-06
GO:0010521 telomerase inhibitor activity 4.76% (3/63) 8.72 0.0 3e-06
GO:2000279 negative regulation of DNA biosynthetic process 4.76% (3/63) 8.72 0.0 3e-06
GO:0016233 telomere capping 4.76% (3/63) 8.92 0.0 3e-06
GO:0098505 G-rich strand telomeric DNA binding 4.76% (3/63) 8.92 0.0 3e-06
GO:0051974 negative regulation of telomerase activity 4.76% (3/63) 8.92 0.0 3e-06
GO:1990414 replication-born double-strand break repair via sister chromatid exchange 4.76% (3/63) 8.54 0.0 4e-06
GO:0016043 cellular component organization 19.05% (12/63) 2.85 0.0 4e-06
GO:0051972 regulation of telomerase activity 4.76% (3/63) 8.41 0.0 4e-06
GO:2000278 regulation of DNA biosynthetic process 4.76% (3/63) 8.27 0.0 5e-06
GO:0032991 protein-containing complex 23.81% (15/63) 2.36 0.0 5e-06
GO:0000783 nuclear telomere cap complex 4.76% (3/63) 8.04 0.0 6e-06
GO:0000782 telomere cap complex 4.76% (3/63) 8.04 0.0 6e-06
GO:0008278 cohesin complex 4.76% (3/63) 8.08 0.0 7e-06
GO:0008150 biological_process 58.73% (37/63) 1.08 0.0 7e-06
GO:0050790 regulation of catalytic activity 7.94% (5/63) 5.2 0.0 7e-06
GO:0032204 regulation of telomere maintenance 4.76% (3/63) 7.86 0.0 8e-06
GO:0065009 regulation of molecular function 7.94% (5/63) 5.14 0.0 8e-06
GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 7.94% (5/63) 5.82 0.0 8e-06
GO:0140358 P-type transmembrane transporter activity 6.35% (4/63) 5.99 1e-06 1e-05
GO:0015662 P-type ion transporter activity 6.35% (4/63) 5.99 1e-06 1e-05
GO:0051276 chromosome organization 9.52% (6/63) 4.35 1e-06 1.1e-05
GO:0051348 negative regulation of transferase activity 4.76% (3/63) 7.63 1e-06 1.1e-05
GO:0022853 active monoatomic ion transmembrane transporter activity 7.94% (5/63) 4.93 1e-06 1.3e-05
GO:0005575 cellular_component 47.62% (30/63) 1.25 1e-06 1.4e-05
GO:0043047 single-stranded telomeric DNA binding 4.76% (3/63) 7.2 1e-06 2e-05
GO:0098847 sequence-specific single stranded DNA binding 4.76% (3/63) 7.2 1e-06 2e-05
GO:0031323 regulation of cellular metabolic process 19.05% (12/63) 2.48 1e-06 2e-05
GO:0060255 regulation of macromolecule metabolic process 19.05% (12/63) 2.49 1e-06 2.1e-05
GO:0019222 regulation of metabolic process 19.05% (12/63) 2.43 2e-06 2.7e-05
GO:0004857 enzyme inhibitor activity 6.35% (4/63) 5.49 2e-06 3e-05
GO:0140678 molecular function inhibitor activity 6.35% (4/63) 5.48 2e-06 3e-05
GO:0022804 active transmembrane transporter activity 11.11% (7/63) 3.57 2e-06 3e-05
GO:0030234 enzyme regulator activity 9.52% (6/63) 4.01 2e-06 3.1e-05
GO:0051053 negative regulation of DNA metabolic process 4.76% (3/63) 6.87 3e-06 3.3e-05
GO:0043086 negative regulation of catalytic activity 4.76% (3/63) 6.82 3e-06 3.5e-05
GO:0044092 negative regulation of molecular function 4.76% (3/63) 6.77 3e-06 3.7e-05
GO:0098772 molecular function regulator activity 9.52% (6/63) 3.92 3e-06 3.8e-05
GO:0017177 glucosidase II complex 3.17% (2/63) 9.36 4e-06 5e-05
GO:0003674 molecular_function 63.49% (40/63) 0.84 5e-06 5.7e-05
GO:0005388 P-type calcium transporter activity 4.76% (3/63) 6.41 7e-06 7.4e-05
GO:0000724 double-strand break repair via homologous recombination 6.35% (4/63) 5.05 7e-06 7.7e-05
GO:0003697 single-stranded DNA binding 6.35% (4/63) 4.97 9e-06 9.1e-05
GO:0016887 ATP hydrolysis activity 9.52% (6/63) 3.65 9e-06 9.1e-05
GO:0000725 recombinational repair 6.35% (4/63) 4.98 9e-06 9.2e-05
GO:0007062 sister chromatid cohesion 4.76% (3/63) 6.2 1e-05 0.000101
GO:0042162 telomeric DNA binding 4.76% (3/63) 6.19 1.1e-05 0.000101
GO:0010048 vernalization response 3.17% (2/63) 8.6 1.3e-05 0.000119
GO:0006491 N-glycan processing 3.17% (2/63) 8.39 1.7e-05 0.000158
GO:0008526 phosphatidylinositol transfer activity 3.17% (2/63) 8.34 1.8e-05 0.000166
GO:0019888 protein phosphatase regulator activity 4.76% (3/63) 5.87 2.1e-05 0.000182
GO:0019208 phosphatase regulator activity 4.76% (3/63) 5.84 2.2e-05 0.000191
GO:0010556 regulation of macromolecule biosynthetic process 15.87% (10/63) 2.35 2.4e-05 0.000201
GO:0005459 UDP-galactose transmembrane transporter activity 3.17% (2/63) 8.09 2.6e-05 0.000217
GO:0042626 ATPase-coupled transmembrane transporter activity 7.94% (5/63) 3.84 2.8e-05 0.00022
GO:0009889 regulation of biosynthetic process 15.87% (10/63) 2.33 2.8e-05 0.000223
GO:0031326 regulation of cellular biosynthetic process 15.87% (10/63) 2.33 2.7e-05 0.000225
GO:0033044 regulation of chromosome organization 4.76% (3/63) 5.7 2.9e-05 0.000227
GO:0006996 organelle organization 11.11% (7/63) 2.98 3.1e-05 0.000238
GO:0005488 binding 46.03% (29/63) 1.03 3.3e-05 0.000251
GO:0006302 double-strand break repair 6.35% (4/63) 4.45 3.7e-05 0.000263
GO:0051052 regulation of DNA metabolic process 4.76% (3/63) 5.59 3.7e-05 0.000265
GO:0015085 calcium ion transmembrane transporter activity 4.76% (3/63) 5.6 3.6e-05 0.000267
GO:0043666 regulation of phosphoprotein phosphatase activity 3.17% (2/63) 7.84 3.7e-05 0.000268
GO:0015399 primary active transmembrane transporter activity 7.94% (5/63) 3.74 3.8e-05 0.000268
GO:0005515 protein binding 23.81% (15/63) 1.67 5e-05 0.000344
GO:0035304 regulation of protein dephosphorylation 3.17% (2/63) 7.6 5.1e-05 0.000346
GO:0008324 monoatomic cation transmembrane transporter activity 7.94% (5/63) 3.64 5.3e-05 0.000355
GO:0051338 regulation of transferase activity 4.76% (3/63) 5.38 5.6e-05 0.000363
GO:0010921 regulation of phosphatase activity 3.17% (2/63) 7.55 5.5e-05 0.000365
GO:0005215 transporter activity 14.29% (9/63) 2.36 6.2e-05 0.000397
GO:0050794 regulation of cellular process 19.05% (12/63) 1.92 6.4e-05 0.000407
GO:0040029 epigenetic regulation of gene expression 4.76% (3/63) 5.3 6.6e-05 0.000409
GO:0006310 DNA recombination 6.35% (4/63) 4.22 6.8e-05 0.000413
GO:0009987 cellular process 39.68% (25/63) 1.11 6.7e-05 0.000416
GO:0006259 DNA metabolic process 11.11% (7/63) 2.79 7e-05 0.000419
GO:0017111 ribonucleoside triphosphate phosphatase activity 9.52% (6/63) 3.11 7.1e-05 0.000423
GO:0000723 telomere maintenance 4.76% (3/63) 5.23 7.7e-05 0.000433
GO:0032200 telomere organization 4.76% (3/63) 5.23 7.7e-05 0.000433
GO:0120014 phospholipid transfer activity 3.17% (2/63) 7.32 7.5e-05 0.000441
GO:0009409 response to cold 3.17% (2/63) 7.31 7.7e-05 0.000443
GO:0051171 regulation of nitrogen compound metabolic process 14.29% (9/63) 2.3 8.2e-05 0.000455
GO:0120013 lipid transfer activity 3.17% (2/63) 7.25 8.3e-05 0.000458
GO:0080090 regulation of primary metabolic process 14.29% (9/63) 2.29 8.8e-05 0.000478
GO:0043231 intracellular membrane-bounded organelle 22.22% (14/63) 1.66 9.7e-05 0.000523
GO:0016462 pyrophosphatase activity 9.52% (6/63) 3.01 0.000103 0.000542
GO:0050789 regulation of biological process 19.05% (12/63) 1.85 0.000103 0.000547
GO:0043227 membrane-bounded organelle 22.22% (14/63) 1.65 0.000105 0.000547
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 9.52% (6/63) 2.99 0.000113 0.000582
GO:0016817 hydrolase activity, acting on acid anhydrides 9.52% (6/63) 2.97 0.000119 0.000606
GO:0015075 monoatomic ion transmembrane transporter activity 7.94% (5/63) 3.36 0.000132 0.000664
GO:0035303 regulation of dephosphorylation 3.17% (2/63) 6.84 0.000146 0.000729
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 4.76% (3/63) 4.86 0.000161 0.000793
GO:0005548 phospholipid transporter activity 3.17% (2/63) 6.74 0.00017 0.00083
GO:0065007 biological regulation 19.05% (12/63) 1.74 0.000199 0.000962
GO:0033043 regulation of organelle organization 4.76% (3/63) 4.64 0.000253 0.001207
GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 3.17% (2/63) 6.42 0.000264 0.001247
GO:0009100 glycoprotein metabolic process 3.17% (2/63) 6.41 0.000268 0.001257
GO:0005338 nucleotide-sugar transmembrane transporter activity 3.17% (2/63) 6.11 0.000403 0.001867
GO:0042254 ribosome biogenesis 3.17% (2/63) 6.06 0.000432 0.001984
GO:0043226 organelle 22.22% (14/63) 1.45 0.000463 0.002085
GO:0032993 protein-DNA complex 4.76% (3/63) 4.33 0.000471 0.002101
GO:0051128 regulation of cellular component organization 4.76% (3/63) 4.33 0.000476 0.002102
GO:0043229 intracellular organelle 22.22% (14/63) 1.45 0.000463 0.002103
GO:0003677 DNA binding 12.7% (8/63) 2.11 0.000517 0.002262
GO:0001042 RNA polymerase I core binding 1.59% (1/63) 10.9 0.000524 0.002271
GO:0006361 transcription initiation at RNA polymerase I promoter 1.59% (1/63) 10.63 0.000629 0.002676
GO:0001181 RNA polymerase I general transcription initiation factor activity 1.59% (1/63) 10.63 0.000629 0.002676
GO:0006139 nucleobase-containing compound metabolic process 15.87% (10/63) 1.76 0.00068 0.00284
GO:0051172 negative regulation of nitrogen compound metabolic process 4.76% (3/63) 4.15 0.000679 0.002861
GO:0140657 ATP-dependent activity 9.52% (6/63) 2.46 0.000796 0.003295
GO:0051336 regulation of hydrolase activity 3.17% (2/63) 5.6 0.000816 0.003319
GO:0006338 chromatin remodeling 4.76% (3/63) 4.06 0.00081 0.003323
GO:0090304 nucleic acid metabolic process 14.29% (9/63) 1.84 0.00087 0.003512
GO:0006325 chromatin organization 4.76% (3/63) 3.94 0.001036 0.00411
GO:0044238 primary metabolic process 30.16% (19/63) 1.07 0.001032 0.004128
GO:0019219 regulation of nucleobase-containing compound metabolic process 11.11% (7/63) 2.12 0.001121 0.004409
GO:0046483 heterocycle metabolic process 15.87% (10/63) 1.66 0.001148 0.004477
GO:0044877 protein-containing complex binding 6.35% (4/63) 3.11 0.001217 0.004709
GO:0070588 calcium ion transmembrane transport 3.17% (2/63) 5.29 0.001249 0.00479
GO:0003682 chromatin binding 4.76% (3/63) 3.83 0.00129 0.004909
GO:0006725 cellular aromatic compound metabolic process 15.87% (10/63) 1.62 0.001364 0.005147
GO:0006816 calcium ion transport 3.17% (2/63) 5.21 0.001388 0.005197
GO:0022857 transmembrane transporter activity 11.11% (7/63) 2.06 0.001414 0.005253
GO:0009974 zeinoxanthin epsilon hydroxylase activity 1.59% (1/63) 9.41 0.001467 0.005363
GO:0072374 carotene epsilon hydroxylase activity 1.59% (1/63) 9.41 0.001467 0.005363
GO:0006281 DNA repair 6.35% (4/63) 3.02 0.001529 0.005547
GO:1901360 organic cyclic compound metabolic process 15.87% (10/63) 1.58 0.00169 0.006086
GO:0034641 cellular nitrogen compound metabolic process 15.87% (10/63) 1.57 0.001794 0.00641
GO:1901505 carbohydrate derivative transmembrane transporter activity 3.17% (2/63) 4.98 0.001885 0.006684
GO:0071824 protein-DNA complex organization 4.76% (3/63) 3.61 0.00197 0.006931
GO:0006974 DNA damage response 6.35% (4/63) 2.89 0.002135 0.007401
GO:0071704 organic substance metabolic process 30.16% (19/63) 0.98 0.002131 0.007441
GO:0016787 hydrolase activity 15.87% (10/63) 1.53 0.002165 0.00745
GO:0022613 ribonucleoprotein complex biogenesis 3.17% (2/63) 4.87 0.002197 0.007451
GO:0015932 nucleobase-containing compound transmembrane transporter activity 3.17% (2/63) 4.87 0.00219 0.007482
GO:0009266 response to temperature stimulus 3.17% (2/63) 4.86 0.00223 0.007508
GO:0046873 metal ion transmembrane transporter activity 4.76% (3/63) 3.51 0.002382 0.007961
GO:0048280 vesicle fusion with Golgi apparatus 1.59% (1/63) 8.7 0.002409 0.007994
GO:0043170 macromolecule metabolic process 23.81% (15/63) 1.13 0.002669 0.008797
GO:0006807 nitrogen compound metabolic process 25.4% (16/63) 1.07 0.002764 0.00892
GO:0051174 regulation of phosphorus metabolic process 3.17% (2/63) 4.7 0.002762 0.008977
GO:0019220 regulation of phosphate metabolic process 3.17% (2/63) 4.7 0.002762 0.008977
GO:0005988 lactose metabolic process 1.59% (1/63) 8.46 0.002827 0.009
GO:0005990 lactose catabolic process 1.59% (1/63) 8.46 0.002827 0.009
GO:0009341 beta-galactosidase complex 1.59% (1/63) 8.36 0.003036 0.0096
GO:0010468 regulation of gene expression 11.11% (7/63) 1.85 0.003241 0.010179
GO:1901702 salt transmembrane transporter activity 4.76% (3/63) 3.35 0.003294 0.010277
GO:0031399 regulation of protein modification process 3.17% (2/63) 4.55 0.003396 0.010526
GO:0008152 metabolic process 30.16% (19/63) 0.91 0.003716 0.011442
GO:0140534 endoplasmic reticulum protein-containing complex 3.17% (2/63) 4.46 0.00383 0.011491
GO:0005516 calmodulin binding 3.17% (2/63) 4.45 0.003856 0.011495
GO:0005319 lipid transporter activity 3.17% (2/63) 4.47 0.003788 0.01151
GO:0050896 response to stimulus 12.7% (8/63) 1.65 0.003828 0.011557
GO:1902494 catalytic complex 7.94% (5/63) 2.27 0.003787 0.011584
GO:0010558 negative regulation of macromolecule biosynthetic process 4.76% (3/63) 3.17 0.004637 0.013735
GO:0031327 negative regulation of cellular biosynthetic process 4.76% (3/63) 3.13 0.005017 0.014767
GO:0009890 negative regulation of biosynthetic process 4.76% (3/63) 3.12 0.005077 0.014849
GO:0006812 monoatomic cation transport 4.76% (3/63) 3.11 0.005197 0.015106
GO:0097361 CIA complex 1.59% (1/63) 7.52 0.005437 0.015707
GO:0015969 guanosine tetraphosphate metabolic process 1.59% (1/63) 7.41 0.005854 0.016706
GO:0022890 inorganic cation transmembrane transporter activity 4.76% (3/63) 3.05 0.005819 0.016707
GO:0034035 purine ribonucleoside bisphosphate metabolic process 1.59% (1/63) 7.39 0.005959 0.0169
GO:0009725 response to hormone 3.17% (2/63) 4.1 0.006189 0.017449
GO:0010605 negative regulation of macromolecule metabolic process 4.76% (3/63) 3.0 0.006449 0.018073
GO:0031324 negative regulation of cellular metabolic process 4.76% (3/63) 2.97 0.006739 0.018772
GO:0000781 chromosome, telomeric region 1.59% (1/63) 7.2 0.006792 0.018808
GO:0009892 negative regulation of metabolic process 4.76% (3/63) 2.97 0.00684 0.018831
GO:0072542 protein phosphatase activator activity 1.59% (1/63) 7.09 0.007313 0.019782
GO:0019211 phosphatase activator activity 1.59% (1/63) 7.09 0.007313 0.019782
GO:0033554 cellular response to stress 6.35% (4/63) 2.39 0.007239 0.019813
GO:0006811 monoatomic ion transport 4.76% (3/63) 2.91 0.007544 0.020291
GO:0009719 response to endogenous stimulus 3.17% (2/63) 3.94 0.007715 0.020633
GO:0051716 cellular response to stimulus 6.35% (4/63) 2.35 0.008 0.021274
GO:0030289 protein phosphatase 4 complex 1.59% (1/63) 6.88 0.008457 0.02236
GO:0008541 proteasome regulatory particle, lid subcomplex 1.59% (1/63) 6.84 0.008665 0.022782
GO:0004864 protein phosphatase inhibitor activity 1.59% (1/63) 6.76 0.009184 0.024013
GO:0005789 endoplasmic reticulum membrane 3.17% (2/63) 3.8 0.009289 0.024152
GO:0019903 protein phosphatase binding 1.59% (1/63) 6.62 0.010119 0.02602
GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity 1.59% (1/63) 6.62 0.010119 0.02602
GO:0019212 phosphatase inhibitor activity 1.59% (1/63) 6.59 0.010327 0.026124
GO:0097428 protein maturation by iron-sulfur cluster transfer 1.59% (1/63) 6.6 0.010223 0.026144
GO:0015318 inorganic molecular entity transmembrane transporter activity 4.76% (3/63) 2.75 0.010318 0.026243
GO:0019902 phosphatase binding 1.59% (1/63) 6.58 0.01043 0.026244
GO:0110165 cellular anatomical entity 30.16% (19/63) 0.77 0.010687 0.026746
GO:0070628 proteasome binding 1.59% (1/63) 6.46 0.01126 0.028031
GO:0022402 cell cycle process 4.76% (3/63) 2.69 0.011576 0.028665
GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1.59% (1/63) 6.39 0.011882 0.029267
GO:0015297 antiporter activity 3.17% (2/63) 3.56 0.012633 0.030953
GO:0044237 cellular metabolic process 22.22% (14/63) 0.92 0.013103 0.03194
GO:0051179 localization 11.11% (7/63) 1.46 0.013204 0.032018
GO:0012507 ER to Golgi transport vesicle membrane 1.59% (1/63) 6.21 0.013435 0.032244
GO:0030662 coated vesicle membrane 1.59% (1/63) 6.21 0.013435 0.032244
GO:0048523 negative regulation of cellular process 4.76% (3/63) 2.59 0.013704 0.032721
GO:0030658 transport vesicle membrane 1.59% (1/63) 6.16 0.013849 0.0329
GO:0016311 dephosphorylation 3.17% (2/63) 3.48 0.013997 0.033083
GO:0061024 membrane organization 3.17% (2/63) 3.47 0.014214 0.033429
GO:0030915 Smc5-Smc6 complex 1.59% (1/63) 6.1 0.014469 0.033522
GO:0106068 SUMO ligase complex 1.59% (1/63) 6.1 0.014469 0.033522
GO:0048519 negative regulation of biological process 4.76% (3/63) 2.57 0.014364 0.033613
GO:0140513 nuclear protein-containing complex 6.35% (4/63) 2.09 0.014667 0.033814
GO:0009628 response to abiotic stimulus 3.17% (2/63) 3.37 0.016289 0.037369
GO:0044085 cellular component biogenesis 3.17% (2/63) 3.35 0.016605 0.037907
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment 1.59% (1/63) 5.86 0.017049 0.038734
GO:0051643 endoplasmic reticulum localization 1.59% (1/63) 5.83 0.017462 0.039289
GO:0061817 endoplasmic reticulum-plasma membrane tethering 1.59% (1/63) 5.83 0.017462 0.039289
GO:1901135 carbohydrate derivative metabolic process 4.76% (3/63) 2.44 0.018044 0.040406
GO:0016117 carotenoid biosynthetic process 1.59% (1/63) 5.7 0.019109 0.042184
GO:0016109 tetraterpenoid biosynthetic process 1.59% (1/63) 5.7 0.019109 0.042184
GO:0046352 disaccharide catabolic process 1.59% (1/63) 5.7 0.019006 0.042357
GO:0043933 protein-containing complex organization 4.76% (3/63) 2.4 0.019464 0.042767
GO:0098687 chromosomal region 1.59% (1/63) 5.63 0.019932 0.043589
GO:0019899 enzyme binding 3.17% (2/63) 3.21 0.02005 0.043644
GO:0015291 secondary active transmembrane transporter activity 3.17% (2/63) 3.2 0.020213 0.043795
GO:0003676 nucleic acid binding 14.29% (9/63) 1.12 0.021549 0.046474
GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 1.59% (1/63) 5.51 0.02178 0.046757
GO:0009313 oligosaccharide catabolic process 1.59% (1/63) 5.48 0.02219 0.047421
GO:0051246 regulation of protein metabolic process 3.17% (2/63) 3.11 0.02288 0.048672
GO:0098655 monoatomic cation transmembrane transport 3.17% (2/63) 3.1 0.02311 0.048939
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
No similar clusters found
Sequences (63) (download table)

InterPro Domains

GO Terms

CAZYmes

Family Terms