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GO:0034038: deoxyhypusine synthase activity (Molecular function)

"Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+." [GOC:pde, RHEA:33299]


There are 889 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_565 Sugarcane pan-transcriptome v1 1.8 % 1.9e-05 0.001921
Cluster_3071 Sugarcane pan-transcriptome v1 50.0 % 0.000113 0.004074
Cluster_5495 Sugarcane pan-transcriptome v1 50.0 % 0.000113 0.002603
Cluster_4569 Sugarcane pan-transcriptome v1 1.16 % 0.004854 0.047662
Cluster_4147 Sugarcane pan-transcriptome v1 1.32 % 0.004291 0.028585
Sequences (889) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms