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GO:0003918: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (Molecular function)

"Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2." [PMID:8811192]


There are 3466 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_466 Sugarcane pan-transcriptome v1 3.28 % 0.0 1e-06
Cluster_6856 Sugarcane pan-transcriptome v1 20.0 % 0.001588 0.039705
Cluster_1503 Sugarcane pan-transcriptome v1 20.0 % 0.001588 0.020647
Cluster_98 Sugarcane pan-transcriptome v1 2.94 % 0.000226 0.005398
Cluster_311 Sugarcane pan-transcriptome v1 1.59 % 0.019829 0.049018
Cluster_5840 Sugarcane pan-transcriptome v1 100.0 % 0.0 0.0
Cluster_6968 Sugarcane pan-transcriptome v1 100.0 % 0.0 0.0
Cluster_431 Sugarcane pan-transcriptome v1 2.76 % 0.0 1e-06
Cluster_9195 Sugarcane pan-transcriptome v1 50.0 % 0.000636 0.00364
Cluster_3668 Sugarcane pan-transcriptome v1 16.67 % 0.001906 0.0343
Cluster_71 Setaria viridis 0.86 % 0.020993 0.037284
Cluster_161 Setaria viridis 0.85 % 0.021351 0.048283
Cluster_311 Brachypodium distachyon 3.39 % 0.000116 0.01196
Cluster_191 Brachypodium distachyon 1.02 % 0.001284 0.010541
Cluster_276 Oryza sativa 1.12 % 0.018828 0.037788
Cluster_176 Oryza sativa 1.61 % 0.01315 0.048217
Cluster_202 Sorghum bicolor 1.82 % 0.014412 0.042666
Cluster_1646 Sugarcane pan-transcriptome v1 1.33 % 0.023561 0.049718
Cluster_8168 Sugarcane pan-transcriptome v1 50.0 % 0.000636 0.013135
Cluster_6257 Sugarcane pan-transcriptome v1 50.0 % 0.000636 0.013347
Cluster_7725 Sugarcane pan-transcriptome v1 50.0 % 0.000636 0.017161
Cluster_7455 Sugarcane pan-transcriptome v1 33.33 % 0.000953 0.008791
Cluster_6631 Sugarcane pan-transcriptome v1 50.0 % 0.000636 0.038135
Cluster_9938 Sugarcane pan-transcriptome v1 50.0 % 0.000636 0.009171
Cluster_5353 Sugarcane pan-transcriptome v1 50.0 % 0.000636 0.021292
Cluster_94 Zea mays 1.12 % 0.000555 0.002072
Cluster_291 Zea mays 1.75 % 0.011488 0.038336
Cluster_24 Zea mays 0.8 % 0.00109 0.007333
Sequences (3466) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms