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GO:0004420: hydroxymethylglutaryl-CoA reductase (NADPH) activity (Molecular function)

"Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H+ + 2 NADPH." [PMID:29224355, RHEA:15989]


There are 1118 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_3072 Sugarcane pan-transcriptome v1 50.0 % 0.000153 0.015615
Cluster_891 Sugarcane pan-transcriptome v1 2.82 % 1.4e-05 0.000999
Cluster_570 Sugarcane pan-transcriptome v1 10.2 % 0.0 0.0
Cluster_58 Sugarcane pan-transcriptome v1 1.89 % 3.2e-05 0.000255
Cluster_860 Sugarcane pan-transcriptome v1 1.56 % 0.004888 0.030991
Cluster_2959 Sugarcane pan-transcriptome v1 50.0 % 0.000153 0.015003
Cluster_196 Oryza sativa 1.96 % 0.003622 0.034697
Cluster_23 Oryza sativa 0.47 % 0.015211 0.04311
Cluster_161 Oryza sativa 1.06 % 0.006669 0.02837
Cluster_883 Sugarcane pan-transcriptome v1 1.15 % 0.006638 0.021216
Cluster_8716 Sugarcane pan-transcriptome v1 50.0 % 0.000153 0.009798
Cluster_8082 Sugarcane pan-transcriptome v1 50.0 % 0.000153 0.009798
Cluster_1309 Sugarcane pan-transcriptome v1 1.35 % 6.2e-05 0.030585
Cluster_4204 Sugarcane pan-transcriptome v1 1.11 % 9.2e-05 0.00314
Cluster_4459 Sugarcane pan-transcriptome v1 3.57 % 9e-06 0.000957
Cluster_2503 Sugarcane pan-transcriptome v1 2.33 % 0.003286 0.043332
Cluster_2906 Sugarcane pan-transcriptome v1 1.75 % 3.7e-05 0.016304
Sequences (1118) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms